Phoenix Therapeutics

Phoenix Therapeutics


Vision

To help introduce quality and affordable stem cell therapies. Our strategy will include :


Autologous Use of Adult Stem Cells :
Initially stem cells will be isolated from adipose tissue (ADSCs) at the bedside, in an air-conditioned side-room or HEPA filterred catheterization laboratory. This will use Stem Cell Stations and the ADSCs will be infused back into patient, in real time without storage, within a 90 minute time period. Immediate, real-time use will allow treatment during the optimal therapeutic window. That is close to times of injury or during relapse phases of chronic diseases when need is greatest and site-of-injury is fresh and differentiated. The local or niche environment in the immediate area of injury influences the behaviour of the stem cells in that area, and this environment is dynamic and constantly changes. Such an approach could be used in open, recalcitrant wounds, reconstructive surgeries, sport's injuries, arthritis, damaged corneas, connective tissue disease and cardiac diseases. This could reduce hospital ward, total surgical and pharmaceutical expenditures, and make immediate and effective therapeutics available in rural populations.

Use of Stem Cell Stations :
This will require a careful approach and a discriminating infrastructure and this is discussed here Infrastructure of Stem Cell Stations (press return blue arrow top left of screen to return to web page)

Use of Air Mailed Stem Cells :
We have a PCT patent pending for the air-mailing of stem cells from the manufacturer to the end user. The patent is explained at PCT Patent for Air Mailing Stem Cells. We hope that this approach will open the clinical use of stem cells to 3rd World markets. When immune naive mesenchymal stem cells (MSCs) are approved and commercially available we hope that this transport package and use of Stem Cell Stations will be an affordable treatment option. MSCs act through paracrine mechanisms, trophic factors released at the site of injury, to assist regeneration by the body's own (endogenous) stem cells. For this reason they are often called "facilitatory stem cells". MSCs could be sent in the transport package and on receipt this would be opened and the stem cells on the alginate nano-scaffold would be applied to open wounds like a band aid. It is better to anchor stem cells in the tissue injury site in a biocompatable, biodegradaeable ISO 10993 accredited gel or scaffold rather than inject them into the circulation. More details of the patent pending are given in the attached Press Release.

Increased Public Awareness of Stem Cells :
PhoenixTherapeutics were the organisers of two International Symposiums on Stem Cells held at the BMW Pavilion in Cape Town Waterfront in 2005 and 2010. They were supported by the National Research Foundation, the Public Understanding of Biotechnology and the Department of Science and Technology. An advertorial was published in Popular Mechanics and short interviews on local radio stations and newspapers, and national television were given. Since then we have been trying to organise an Open Day to increase public awareness of stem cells. This has not been possible. To encourage public participation a short history of adult stem cells is available at the link below :

A Short History of Stem Cells

This website also links to a blog about adult stem cells. This blog can be visited at :
http://phoenixtherapeutics.blogspot.com


The blogspot contains several poems about stem cells. Others will I hope also interact on an anonymous basis and add comments, poems or drawings and paintings. I hope that some of the material may be useful for anyone organising a public awareness event.
Should you have questions or feedback please write to : info@phoenixtherapeutics.co.za.
Further details about Phoenix Therapeutics are given at this link :